One of the major advances in anti-aging science is the discovery of healthy attributes that we can adopt until the journey reaches tangible results. Caloric restriction, or fasting can have a most profound effect on the body and mind. This also happens to activate AMPK as well as a host of nutrients like: Gynostemma pentaphyllum (an herb), Hesperidin, Rose hips, which contain the compound trans-tiliroside, Resveratrol, Quercetin, Genistein, Epigallocatechin gallate (EGCG), Capsaicin (from red chilies), Curcumin, Ginsenosides from Panax ginseng and Alpha-lipoic acid.
AMPK (AMP-activated protein kinase) is an enzyme that serves as an energy-sensing switch that informs the cells when to store energy and generate energy-containing molecules such as fat, and when to break down existing energy stores. AMPK signaling declines during aging.
Chronic intake of too many calories can impair AMPK activity. AMPK activity declines under conditions of excessive caloric and carbohydrate intake. Conversely, caloric restriction increases AMPK activity.
We can supplements with the right nutrients and practice caloric restriction to maintain a healthy weight.