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Life Extension

High Potency Optimized Folate L-Methylfolate

High Potency Optimized Folate L-Methylfolate

Regular price $13.50 USD
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High Potency Optimized Folate L-Methylfolate 
8500 mcg DFE, 30 vegetarian tablets

High Potency Optimized Folate is a cardiovascular health supplement that also supports cognitive health and more with 8500 mcg of metabolically active 5-MTHF.
Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with both cardiovascular and cognitive health. Folate, a B vitamin, helps maintain homocysteine levels already within normal range. However, not everyone can efficiently convert folate to its biologically active form. Life Extension's formula provides 5-MTHF, so you don’t have to.

The 5-MTHF folate in High Potency Optimized Folate is an ultra-bioavailable form of the B-vitamin commonly called folic acid.

High Potency Optimized Folate Benefits

  • Super high-potency dose of bioavailable 5-MTHF folate
  • Supports both cardiovascular & cognitive health
  • Helps maintain already-healthy homocysteine levels
  • 5-MTHF folate overcomes the enzyme inefficiency roadblock

Folic acid is the most common form of folate supplements. Once ingested, your body is supposed to convert folic acid, a synthetic version of folate, into 5-methyltetrahydrofolate, or 5-MTHF. But research shows that many people lack sufficient activity of the enzyme that's necessary to convert folic acid to 5-MTHF. A more useful approach is to take 5-MTHF directly.

5-MTHF, homocysteine & cardiovascular health

Folate helps maintain healthy homocysteine levels already within the normal range. By helping to inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular health biomarker. And 5-MTHF has been shown to be more bioavailable than folic acid in some studies.

5-MTHF, homocysteine & cognitive health

5-MTHF's greater bioavailability is especially important for people who don't have enough activity of the enzyme necessary to convert folic acid to its biologically active form. Since people with elevated homocysteine levels have a greater risk of cognitive decline, the increased efficiency of 5-MTHF in supporting healthy folate status is especially crucial for aging individuals. 

Take alone or with B12 for enhanced effect

The RDA for folate for non-pregnant or lactating adults is 400 mcg a day, but this high-potency formula provides 8500 mcg of this super-bioavailable form of folate. For even greater health benefits, take 5-MTHF folate with methylcobalamin (the active form of vitamin B12), vitamin B6 and/or riboflavin.

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

Serving Size 1 vegetarian tablet

Amount Per Serving

Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt]

8500 mcg°

Other ingredients: microcrystalline cellulose, dicalcium phosphate, stearic acid, croscarmellose sodium, silica, vegetable stearate.

°DFE (dietary folate equivalents)

Non-GMO

Dosage and Use

  • Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.

Caution

Do not use this product if treated with methotrexate, fluorouracil, phenytoin, phenobarbital, primidone, or levodopa prior to consultation with your personal physician.

 

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SHIPPING

We promptly process your order in 1 business day, M-SAT, and ship within North America and the MENA region. We use USPS and UPS for deliveries in the USA with about 3-5 days transit time, and UPS, DHL or other providers for shipments outside the USA with a delivery time frame of about in 5-7 days.

We charge USPS or UPS rates. Free shipping for US domestic orders over $175 until further notice. Flat rates for outside of the US are $35 for shipping to Canada, (We are not currently shipping to Mexico), $35 flat for Bermuda and Greenland for orders above $100 and $95 for the MENA region for orders above $100.

Payment is with a credit card, debit card, Amazon Pay or any other payment service that is offered at checkout.

Curbside pick-up is available at our Nashville, TN office location. Choose Pick up instead of Ship at checkout.